Garaci E.
Editor's note
Garaci's history of how thymosin alpha-1 got from Goldstein's thymus extracts to an actual marketed drug in 35-plus countries. Mostly relevant for sepsis and chronic-viral-infection use cases. Editorial-adjacent — pair with primary trial data.
Related literature
Khavinson V.Kh., Bondarev I.E., Butyugov A.A.
Khavinson's foundational paper claiming epithalon upregulates telomerase in human somatic cells. Provocative, Soviet-school methodology, repeatedly cited and rarely replicated outside the original group — read it knowing both.
Yoshino M. et al.
Ten weeks of 250 mg/day NMN in 25 prediabetic women improved insulin-stimulated glucose disposal by 25±7% — comparable to a major weight loss. No effect on body weight, blood pressure, lipids, or hepatic fat. The most-cited piece of human NMN data; small, female-only, single-site.
Martens C.R. et al.
The crossover trial that became the floor for every NR claim. 1,000 mg/day for six weeks safely raised whole-blood NAD+ — but the secondary outcomes (blood pressure, arterial stiffness, performance) moved only modestly. Confirms biology, not clinical benefit.
Cobb L.J. et al.
The Cohen/Barzilai group's case that circulating humanin tracks with biological age and falls in disease states. Mostly observational human data plus mechanistic mouse work; humanin therapeutics in humans don't yet exist outside trial protocols.
001 — Independent
SavePeptides lists vendors after an initial review and distinguishes verified vendors where additional checks have been completed. We may earn commissions from referral links, and sponsored placements will be clearly disclosed.
002 — Vendor-funded
SavePeptides is free for buyers. We may earn a commission when you order through our links, but we do not lock deals behind a paywall, require an email to view codes, or inflate comparison prices.
003 — Research use
SavePeptides surfaces vendor, pricing, and coupon information for research compounds. These products are not intended, approved, or recommended for human consumption. Our content is informational only and does not constitute medical advice.